Welcome to Bamba-laboratory!!
The keyword in our laboratory is metabolomics.
We aim to (i) develop the leading-edge analytical techniques and (ii) educate professionals of analytical chemistry who can work on the global scale.
We are not only just satisfied with being able to use the equipment or reproduce the experimental protocol, but also we are interested in the principles and mechanisms of the analytical systems, that is because we are trying to create a new analytical tool that can open the new research fields.
“Analysis is about love and guts.”
“Learn well, play well.”
If you are interested in our laboratory, please contact us and visit our laboratory.
Research in our laboratory
Genomic information is translated into proteins via a transcriptional process. The translated enzymatic proteins are then used to synthesize metabolites necessary for biological systems. These whole set of metabolites are called “metabolome“, and the technology and research field to analyze the metabolome is called “metabolomics“. In our laboratory, we are working on the development of techniques for metabolomics and the application of metabolomics to better understanding of biological systems.
Metabolomics provides a comprehensive view of the chemical changes of low-molecular-weight compounds synthesized by enzymatic proteins. Metabolome is the closest means of high-resolution phenotyping to biological events. In other words, the metabolome is a useful indicator that can be used as a molecular phenotype of biological activity as a result of complex and continuous changes caused by genome translation/transcription or environmental factors.
In our laboratory, we have developed highly sensitive and quantitative metabolome analysis methods using chromatographs and mass spectrometers, which enabled to observe the real of metabolome in cells with high precision.
And we are applying the developed method to variety of studies including the disease, food, molecular cell biology, and so on.
In addition, we are trying to integrate metabolomics with other omics such as genomics, epigenomics, transcriptomics, and proteomics. Please see our PUBLICATIONS for more details.